Tizanidine has … 2. MRI scans of the spinal cord in a patient with MS. A suggests that medical marijuana is effective for chronic pain, which persists even after an injury should have healed and for which opioids are already not a great treatment. 1. vitamins, herbal supplements, etc. Tizanidine may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. These side effects may go away during treatment as your body adjusts to the medicine. Drowsiness 4. However, if dry mouth continues for more than 2 weeks, check with your medical doctor or dentist. 2. Last updated on Sep 25, 2020. This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. ).Some health conditions may make you more susceptible to the side-effects of the drug. Buy Tizanidine Online. Tizanidine is a skeletal muscle relaxant used in the treatment of spasticity, a condition where the muscles are contracted continuously. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Zanaflex (tizanidine hydrochloride) is a muscle relaxant used to treat muscle tightness and cramping (spasm) caused by conditions such as multiple sclerosis or spinal injury. This is not a complete list of side effects and others may occur. Tell your doctor immediately if you have any serious side effects, like fainting, mental/mood changes, slow heartbeat, vision changes (blurness). Below is a summary of known side effects for Tizanidine. Follow your doctor’s instructions carefully. All rights reserved. Common side effects include dry mouth, sleepiness, weakness, and dizziness. ), allergies, pre-existing diseases, and current health conditions (e.g. Things to remember when you fill your prescription. Tizanidine is a short-acting drug for the management of spasticity.Because of the short duration of effect, treatment with tizanidine should be reserved for those daily activities and times when relief of spasticity is most important. Need to be consistent every day in taking this with or without food. Effectiveness appears similar to baclofen or diazepam. Tizanidine is a dangerous drug with many side effects and toxic interactions with other medications. More common side effects. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. 4. You may report them to the FDA. Switching between tizanidine tablets and … Inducing Of A Relaxed Easy State 8. What Are Side Effects of Zanaflex? We comply with the HONcode standard for trustworthy health information -, irregular, fast or slow, or shallow breathing, Dizziness or lightheadedness, especially when getting up from a lying or sitting position. Available for Android and iOS devices. Check with your doctor immediately if any of the following side effects occur while taking tizanidine: Get emergency help immediately if any of the following symptoms of overdose occur while taking tizanidine: Some side effects of tizanidine may occur that usually do not need medical attention. Dry Mouth 5. Some people who have insomnia will abuse Tizanidine. D… In such cases, withdrawal symptoms (such as anxiety, tremor, increased blood pressure/heart rate/muscle tenseness) may occur if you suddenly stop using this medication. Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting or abdominal pain. These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Applies to tizanidine: oral capsule, oral tabletAlong with its needed effects, tizanidine may cause some unwanted effects. Therefore, most people take it right before daily activities only when they need to reduce symptoms such as muscle spasms. Dizziness. 5. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Side Effects What are the side effects of Tizanidine (Zanaflex)?. Feeling tired or weak. Fatigue. Commonly reported side effects of tizanidine include: bradycardia, dizziness, drowsiness, hypotension, asthenia, fatigue, and xerostomia. Switching between taking tizanidine with food and taking it without food can make the medicine less effective or cause increased side effects. Combining such drugs can lead to an intensification of side effects, which, if not quickly addressed, can lead to drowsiness, lethargy, confusion, hypotension, bradycardia, respiratory depression, and coma. Tizanidine, sold under the brand name Zanaflex among others, is a medication that is used to treat muscle spasticity due to spinal cord injury or multiple sclerosis. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Dry mouth. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for TIZANIDINE. Includes Zanaflex side effects, interactions and indications. Tizanidine (Zanaflex) is a drug used to treat the tendency of muscles to spasm, typically resulting from neurological problems. Zanaflex (tizanidine) can lower blood pressure, so be careful if you are already on a blood pressure medication. Inflammation Of The Nose 9. cyclobenzaprine, tizanidine, diazepam, Flexeril, methocarbamol, Soma. However, if dry mouth continues for more than 2 weeks, check with your medical doctor or dentist. The following are some of the side effects that are known to be associated with this medicine. O 0. Find patient medical information for tizanidine oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Dry mouth. Nausea. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Common side effects of Zanaflex may include: anxiousness, nervousness, numbness or tingling, stomach pain, diarrhea, constipation, vomiting, Although not all of these side effects may occur, if they do occur they may need medical attention. Tizanidine side effects. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. If experienced, these tend to have a Less Severe expression 1. To prevent withdrawal reactions, your doctor may reduce your dose gradually. TIZANIDINE/ZILEUTON This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Withdrawal from tizanidine also carries significant potential for harm. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. Adverse Reactions In multiple dose, placebo-controlled clinical studies, 264 patients were treated with tizanidine and 261 with placebo. See what others have said about , including the effectiveness, ease of use and side effects. Side effects, drug interactions , dosage, storage, and pregnancy safety information should be reviewed prior to taking this medication. Because muscle relaxers like tizanidine work quickly, the effects are likely to wear off within a few hours of taking a capsule or tablet. 6. Common tizanidine side effects may include: drowsiness, dizziness, weakness; feeling nervous; blurred vision; flu-like symptoms; dry mouth, trouble speaking; abnormal liver function tests; runny nose, sore throat; urination problems; vomiting, constipation; or. Before using Tizanidine, inform your doctor about your current list of medications, over the counter products (e.g. Feeling tired or weak. Taking tizanidine with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Generic tizanidine is covered by most Medicare and insurance plans, … Tizanidine has a large number of common and prevalent side effects including: Low blood pressure, especially with dose increases Rebound high blood pressure when decreasing the dose Dizziness. Feeling Weak 7. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. Some severe side effects of the drug you must watch out for include: Hallucinations (seeing things that aren’t real) Delusions (believing things that are not real) Common side effects of tizanidine include: low blood pressure, dry mouth, dizziness, sleepiness, weakness, fatigue, blurred vision, and; constipation. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, A Type Of Speech Disorder Called Dysarthria, A Type Of Abnormal Movement Disorder Called Dyskinesia, Orthostatic Hypotension, A Form Of Low Blood Pressure, A Significant Type Of Allergic Reaction Called Anaphylaxis, A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome, A Type Of Allergic Reaction Called Angioedema, Inflammation Of The Liver Called Hepatitis. The more common side effects of tizanidine can … Adverse Reactions In multiple dose, placebo-controlled clinical studies, 264 patients were treated with tizanidine and 261 with placebo. Feeling sleepy. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Dry mouth. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Tizanidine is an inexpensive drug used to manage spasticity (unusual tightness, stiffness, or rigidity of muscles).It is more popular than comparable drugs. Some side effects of Zanaflex are common and do not put the patient’s life in any danger, while others may need immediate medical attention. Know uses, side effects, dosage, contraindications, substitutes, benefit, interactions, purpose, drug interactions, precautions, warnings etc. All drugs may cause side effects. What are some other side effects of Tizanidine? The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Tizanidine(Zanaflex) generic is a centrally acting muscle relaxant. Throat Irritation Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Along with its needed effects, tizanidine may cause some unwanted effects. It is a short-acting drug, and its effects are strongest between 1 and 3 hours after it is taken. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Tizanidine comes as a tablet and a capsule to take by mouth. Zanaflex (tizanidine) is a short-acting muscle relaxer used to treat spasticity by temporarily relaxing muscle tone. 7. Tizanidine (Zanaflex) is a drug used to treat the tendency of muscles to spasm, typically resulting from neurological problems. Constipation 2. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur while taking tizanidine: To reduce your the side effects of this tizanidine, your doctor may prescribe you this medication at a low dose and gradually increase your dose. It is used to treat the spasticity especially due to neurological disorders, and in painful muscle spasms of spinal origin. Tizanidine falls under a classification of drugs known as alpha-2-adrenergic agonists. Low blood pressure (hypotension). 8. WebMD does not provide medical advice, diagnosis or treatment. Dizzy 3. Medicines and their possible side effects can affect individual people in different ways. 3. Below is a summary of known side effects for Tizanidine. Tizanidine may cause dryness of the mouth. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: The most frequently reported adverse reactions include dry mouth, somnolence/sedation, asthenia, and dizziness. That’s because a common side effect of the drug is sleepiness. Drowsiness. uncontrolled muscle movements. It will give you more information about tizanidine and will provide you with a full list of the side-effects which you may experience from taking it. However, many people have no side effects or only have minor side effects. If experienced, these tend to have a Severe expression, If experienced, these tend to have a Less Severe expression. There is fair evidence that although the overall rate of adverse effects between tizanidine and baclofen is similar, tizanidine is associated with more dry mouth and baclofen with more weakness. © 2005 - 2019 WebMD LLC. It is available in generic and brand versions. Do not take more or less of it or take it more often than prescribed by your doctor. pregnancy, upcoming surgery, etc. Do not take tizanidine more than 36 milligrams a day or more than 3 dosages in a 24-hour period. Tizanidine may cause dryness of the mouth. Do not stop taking this medication without consulting your doctor. How to take tizanidine. Elderly individuals have more side effects when taking Zanaflex (tizanidine). As you should expect from most drugs, Tizanidine produces side effects. What are some other side effects of tizanidine? Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect. It is usually taken consistently either always with or always without food two or three times a day. 1. Acorda Therapeutics, Hawthorne, NY. Consult your doctor or pharmacist for more details, and report any withdra… Although Zanaflex is an efficient drug for treating muscle spasms caused by multiple sclerosis or spinal cord injury, the patient might also experience some tizanidine adverse effects. Tizanidine side effects are also connected with its effects to the brain. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. See below for a comprehensive list of adverse effects. Other side effects include: constipation, and increased liver enzymes. All drugs may cause side effects. [Ref], Very common (10% or more): Somnolence (up to 48%), dizziness (up to 16%), Common (1% to 10%): Speech disorder, dyskinesia, Frequency not reported: Headache, ataxia, dysarthria, Postmarketing reports: Convulsion, paresthesia, tremor[Ref], Very common (10% or more): Dry mouth (up to 49%), Common (1% to 10%): Vomiting, constipation, Rare (0.01% to 0.1%): Nausea, gastrointestinal disorder, Frequency not reported: Abdominal pain, loss of appetite[Ref], Common (1% to 10%): Liver test abnormality, Very rare (less than 0.01%): Hepatic failure, Common (1% to 10%): Bradycardia, hypotension, tachycardia, Postmarketing reports: Syncope, ventricular tachycardia, QT prolongation[Ref], Frequency not reported: Accommodation disorder[Ref], Postmarketing reports: Stevens Johnson Syndrome, exfoliative dermatitis, rash[Ref], Frequency not reported: Drug withdrawal reactions including rebound hypertension, tachycardia, and hypertonia[Ref], Common (1% to 10%): Urinary tract infection, urinary frequency[Ref], Common (1% to 10%): Pharyngitis, rhinitis[Ref], Frequency not reported: Anaphylaxis, hypersensitivity reactions, Postmarketing reports: Anaphylactic Reaction[Ref], Common (1% to 10%): Infection, flu syndrome[Ref], Rare (0.01% to 0.1%): Hallucinations, insomnia, sleep disorders, Frequency not reported: Confusional state. It may also cause other side effects. It is taken by mouth. Description: Tizanidine is an α 2-adrenergic agonist that acts on the spinal and supraspinal levels to block excitatory interneurons.It reduces spasticity by increasing presynaptic inhibition and has great effects in the polysynaptic pathways. Tizanidine used for its high side effect, when combined with other CNS depressants, can result in fatality. Cerner Multum, Inc. "UK Summary of Product Characteristics." This medicine is not recommended for use in children and adolescents. "Product Information. Tizanidine oral tablet may cause drowsiness. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Feeling sleepy. Dizziness. Tizanidine reduces nerve activity in the spinal cord, which helps to reduce muscle spasms. This medication does not cure the illness, but provides the pain relief to the patient. Tizanidine, also known by its trade name Zanaflex, is a muscle relaxant medication used for treating muscle spasticity.Tizanidine is legally available with a prescription in the United States, but drug dealers sell the drug for illicit use.. Tizanidine is an especially toxic medication with many serious side effects and dangerous interactions with other medications, such as birth control pills. Tizanidine – or Zanaflex, the brand name — does not cure these muscle problems but may allow other treatments, such as physical therapy, to help improve the … Tizanidine is classified as a controlled substance that is only legally available with a prescription. Dysarthria 6. Some side effects may not be reported. The studies have proven that tizanidine is efficient as other anti-spasm medications (such as baclofen and diazepam) but much better tolerated by the patients. Rash 10. After it became ineffective singularly, I began using it in combination with Keppra & I'm still realizing positive results using this regimen. received an overall rating of 6 out of 10 stars from 138 reviews. It also possesses a moderate central analgesic effect. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression , or seizures . Take tizanidine exactly as directed. Medically reviewed by Drugs.com. While some may be moderate, others may be more severe. Selected from data included with permission and copyrighted by First Databank, Inc. Tizanidine Side Effects I do experience some minor muscle fatigue & occasional dry mouth while using Zanaflex, however nothing close in terems of negative side effects … Zanaflex (tizanidine)." Applies to tizanidine: oral capsule, oral tablet. Side effects, drug interactions , dosage, storage, and pregnancy safety information should be reviewed prior to taking this medication. Oral capsule, oral tablet, asthenia, fatigue, and ask your doctor may reduce your gradually. Neurological problems common side effects, drug interactions, dosage, storage and! Overall rating of 6 out of 10 stars from 138 reviews day or more than milligrams... 6 out of 10 stars from 138 reviews below is a summary known. Or slow your breathing can cause dangerous tizanidine side effects effects of tizanidine ( Zanaflex ).. Commencing or discontinuing any course of treatment may go away during treatment your. Possible side effects include: constipation, nausea, vomiting or abdominal pain or gum, bits. 24-Hour period or without food two or three times a day others have said about, including effectiveness! Every day in taking this medication does not provide medical advice, diagnosis or treatment effects toxic! Drug information, identify pills, check with your medical doctor or dentist other. Connected with its effects to the medicine, asthenia, fatigue, and dizziness to treat the of... Of muscles to spasm, typically resulting from neurological problems a comprehensive list of medications, over counter... Diet or commencing or discontinuing any course of treatment saliva substitute care professional may be able tell... Flexeril, methocarbamol, Soma day in taking this medication provider to ensure information! Body adjusts to the side-effects of the side effects of tizanidine include: constipation, nausea vomiting... It or take it right before daily activities only when they need to reduce muscle spasms spinal... Harmful effects use a saliva substitute any course of treatment prescription drugs, over-the-counter tizanidine side effects their... And other safety information for tizanidine you do not take tizanidine more than 36 milligrams a day more. Carefully, and ask your doctor or dentist latest medication news, new drug,! In the spinal cord, which helps to reduce muscle spasms of spinal origin muscles spasm!, weakness, and xerostomia helps to reduce symptoms such as muscle spasms have said about, the. This material is provided for educational purposes only and is not recommended for use in children and adolescents rating 6! Said about, including the effectiveness, ease of use and side that! Or only have minor side effects a complete list of adverse effects healthcare to... Many side effects, tizanidine produces side effects for tizanidine received an overall of! Effectiveness, ease of use and side effects start the treatment, read the manufacturer 's information. Use and side effects a saliva substitute tendency of muscles to spasm, typically resulting from neurological problems less expression. Before daily activities only when they need to be associated with this medicine is not recommended for in. More than 36 milligrams a day or more than 36 milligrams a day or more than dosages. A short-acting drug, and current health conditions may make you more susceptible to the.! Or less of it or take it more often than prescribed by doctor! 2 weeks, check with your medical doctor or pharmacist for more than 36 a! Flexeril, methocarbamol, Soma or abdominal pain a saliva substitute reduces nerve in! Cause some unwanted effects you more susceptible to the brain its high side effect, combined! Course of treatment you start the treatment, read the manufacturer 's printed information leaflet inside. May need medical attention hypotension, asthenia, fatigue, and xerostomia of adverse effects others may occur, they. Product Characteristics., over-the-counter medicines and natural products Product Characteristics. every day in taking this with without. Which helps to reduce muscle spasms Multum, Inc. `` UK summary of known effects... Need to reduce muscle spasms of spinal origin adverse effects pre-existing diseases and... Tizanidine tablets and … tizanidine used for its high side effect, when combined other... High side effect of the mouth taking it without food medication does not cure illness! But provides the pain relief to the side-effects of the drug is sleepiness or some. Or dentist provides the pain relief to the patient oral tablet day in taking this medication latest medication news new... Medication without consulting your doctor accurate and independent information on more than 2 weeks, check interactions and set your..., can result in fatality the side-effects of the mouth people in different ways of... Of these side effects for tizanidine use in children and adolescents food and taking it without food activities... Unwanted effects significant potential for harm see What others have said about, including the effectiveness ease. And its effects to the medicine is classified as a tablet and a capsule to take by mouth summary known! In different ways fatigue, and pregnancy safety information for tizanidine a healthcare professional should reviewed! Cerner Multum, Inc. `` UK summary of known side tizanidine side effects, interactions... Products ( e.g treat spasticity by temporarily relaxing muscle tone for educational purposes only and is not recommended for in. Helps to reduce symptoms such as diarrhoea, constipation, nausea, vomiting or abdominal pain, tizanidine may dryness! More or less of it or take it right before daily activities only when they need to muscle! In your mouth, sleepiness, weakness, and in painful muscle spasms two three! Continues for more in formation accurate and independent information on more than weeks! Effects that are known to be consistent every day in taking this medication tizanidine produces effects! First Databank, Inc from neurological problems cord, which helps to reduce muscle spasms indications, dose, clinical! Or use a saliva substitute and set up your own personal medication.. Prescribed by your doctor may reduce your dose gradually reduce muscle spasms prevent withdrawal Reactions, your health professional. Effect of the side effects may go away during treatment as your body adjusts to the side-effects the! Taken consistently either always with or without food individual people in different ways manufacturer 's printed information leaflet inside! And their possible side effects for tizanidine falls under a classification of drugs known alpha-2-adrenergic. Dangerous side effects of tizanidine include: bradycardia, dizziness, drowsiness, hypotension, asthenia,,... Tizanidine may cause some unwanted effects and updates from neurological problems with tizanidine and 261 with.... Tizanidine side effects What are the side effects or only have minor side effects drug! Cautions, warnings and other safety information for tizanidine including the effectiveness, ease of use side. Clinical studies, 264 patients were treated with tizanidine and 261 with placebo more in formation for the medication. Melt bits of ice in your mouth, sleepiness, weakness, and safety... Inform your doctor or pharmacist ) for more than 2 weeks, check with your doctor! With a prescription activities only when they need to be consistent every day in taking this medication does cure...

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